Cholera is an acute infectious disease caused by Vibrio cholerae. It remains a major public health threat in developing countries due to inadequate availability of safe water and sanitation facilities. Cholera is one of the most prevalent water-related infections in many regions of the world, specifically in South Asia such as Bangladesh and India, sub-Saharan Africa, and Latin America. First prevalence in the Ganges, India in 1817, cholera has presence more than seven times and caused tremendous disasters to humankind. In order to promote the prediction and early warning of cholera breakouts, many studies have investigated. The majority of cholera outbreaks originate in coastal regions, indicating a strong association between environment and the cholera disease. Especially, environmental Factors such as unsafe water supply, poor sanitation facilities, unhygienic food, poor living condition, constant changeable climate influencing cholera epidemic and epidemic region are located near the coastal area. So during episodes prevailing warm air temperature with low River flows and create a favourable environmental condition for the growth of cholera. Climate can affect disease transmission in a variety of ways. Sometimes due to heavy rainfall, the breakdown of sanitary infrastructure because of accelerates human activities. As result, seawater carrying bacteria in the land. Due to high air temperatures create environmental conditions favourable for bacterial growth and above normal rainfall in combination with appropriate transmission mechanisms such as poor availability of safe water and destruction of sanitation. The frequency of occurrence of cholera is significantly greater at temperatures above 19 °C. Flooding can result in sewage overflow and widespread water contamination. In 1994, the cholera outbreak is epidemic in Surat a small city of Gujarat. This was example of flooding related cholera . Cholera is also one of public health issue and proper care and program get improvement in mortality rate.